Modafinil is a powerful sleep aid that can boost alertness and focus. But it can also raise health risks when mixed with the wrong substances, such as alcohol and caffeine.
Serious skin reactions can occur weeks to months after starting this medicine. Contact your doctor right away if you have fevers and flu-like symptoms; blistering, peeling, or loosening of the skin; or a rash with red spots.
Alcohol
Alcohol can interfere with modafinil australia online, and this combination may lead to unpredictable effects. This can include nausea, heart palpitations, anxiety, or insomnia. It’s important to talk to a doctor before consuming alcohol while taking this medicine.
Modafinil works by inhibiting dopamine reuptake in the brain to promote alertness and improve cognitive function. In contrast, alcohol depresses the central nervous system and can impair judgment and motor skills.
Medical professionals advise waiting at least 24 hours after taking modafinil before drinking alcohol. This will give the drug time to metabolize, and it will reduce the risk of unwanted side effects. However, this recommendation is not always practical for many individuals.
Caffeine
Modafinil and caffeine can interact, intensifying the side effects of both drugs. Avoid consuming large amounts of caffeinated foods or beverages (coffee, tea, energy drinks, chocolate) while taking modafinil.
Both stimulants can cause high blood pressure, jitteriness, anxiety, trouble sleeping and other symptoms if taken together. This combination may increase your risk for heart problems, especially if you have heart disease or other health issues.
Grapefruit juice can decrease the effectiveness of Modafinil because it inhibits CYP3A4, an enzyme that breaks down many medications. Ask your doctor before significantly altering your intake of grapefruit juice while taking modafinil. Other food, supplements and recreational substances also can interfere with the effectiveness of this medication. Tell your doctor about all your current medications, supplements and recreational substances before starting a new one.
Birth Control
With perfect use, combination birth control pills (estrogen plus progestin) are about 99% effective at preventing pregnancy. But taking certain medications, supplements, or other substances can interfere with the pill's effectiveness.
If you take medication like Actos (pioglitazone) or Tracleer (bosentan) that affects your bowel movements, it can decrease the pill's effectiveness by making it harder for your body to absorb it. This is especially true if you have severe vomiting or diarrhea for more than two days.
Continuous-dosing and extended-cycle pills can reduce bleeding and prevent pregnancy by shortening the number of menstrual periods you have each year. But they're not the best choice for everyone, and you need to use a backup method of birth control. Talk to your doctor for more information.
Other Medicines
Many prescription medicines and some over-the-counter (OTC) medicines, vitamins, herbal, and dietary supplements can interact with modafinil. Tell your doctor about all the medicines you take, including OTC and nonprescription drugs.
This medicine may cause serious allergic reactions, including angioedema (swelling of the throat and face), and other severe skin reactions. Get emergency medical help if you have symptoms like hives, itchy skin rash, fever, and trouble breathing.
Modafinil (Modalert 200 mg) promotes wakefulness and is used to treat excessive daytime sleepiness caused by narcolepsy, obstructive sleep apnea, and shift work sleep disorder. It does not treat the underlying condition and should be used along with other treatments for narcolepsy or obstructive sleep apnea. It is also not a substitute for alertness-enhancing medicines such as epinephrine or amphetamine and should be avoided by people with heart disease, high blood pressure, or other heart problems.
Pregnancy
Modafinil (Provigil, Nuvigil) and armodafinil are a type of psychostimulant that can help increase wakefulness in people with sleep disorders, such as narcolepsy. It is also used for ADHD and fatigue associated with multiple sclerosis. These medications are categorized as "Class C" meds, which means there is limited or no evidence that they cause harm to the fetus, but some obstetricians do not recommend them for pregnancy.
Modafinil may interact with certain birth control medications and reduce their effectiveness. Talk to your doctor about using a different method of birth control while taking this medication and for one month afterward. CYP3A4 enzyme inhibitors like ibuprofen, naproxen, and tamoxifen can interact with modafinil to make it less effective as well.
A Danish study that used national health registries found that first-trimester exposure to modafinil and armodafinil was associated with an increased risk of major congenital malformations, but the data are limited and no clear pattern has been identified.
