Mixing alcohol and Adderall is not safe and can be very dangerous. Adderall is a stimulant, while alcohol is a depressant — combining the two sends mixed signals to the body. This can mask the effects of intoxication, leading to excessive drinking, dehydration, and a higher risk of alcohol poisoning. The combination also increases strain on the heart and nervous system, potentially causing high blood pressure, irregular heartbeat, anxiety, or even heart attack. Additionally, both substances affect judgment and coordination. It’s best to avoid using alcohol and Adderall together and follow your doctor’s instructions for safe medication use.