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Peripheral edema is a known side effect of Pregabalin 300 mg, caused by increased fluid retention and changes in blood vessel permeability. While usually mild, it can feel uncomfortable for some users. Staying active, reducing salt intake, elevating your legs, and monitoring weight changes can help prevent or minimize swelling. Patients with heart or kidney conditions should follow their doctor’s guidance closely, as they may be more prone to edema. Always report sudden or severe swelling to a healthcare professional.

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