1. Introduction
Everyone faces mild to moderate pain—headaches, muscle soreness, menstrual cramps, or low-grade fever—at some point. Over-the-counter pain relief is often sufficient for these common ailments. One of the most trusted options is Brufen 400 mg, a powerful form of ibuprofen in the NSAID (non-steroidal anti-inflammatory drug) family. With combined analgesic, anti-inflammatory, and antipyretic (fever-reducing) benefits, it stands out as a go-to for many.
In this comprehensive guide, you’ll learn:
What Brufen 400 mg is and why it works
Best pain types for its use
Proper dosage and timing
Safety measures and precautions
Tips on optimizing effectiveness
When to consult a healthcare professional
By the end, you’ll know whether Brufen 400 mg is the right choice for your next bout of pain relief—and how to use it responsibly.
2. What Is Brufen 400 mg?
Brufen 400 mg is a tablet of ibuprofen with the brand name, having 400 mg of active drug. Ibuprofen blocks the action of COX-1 and COX-2 enzymes, lowering prostaglandins—chemical messengers that cause pain, inflammation, and fever. Its double action makes every tablet useful for:
Pain relief (analgesia)
Inflammation reduction (anti-inflammatory)
Lowering fever (antipyretic)
It provides a strong alternative to easier ones such as paracetamol without compromising on a decent safety profile when used appropriately.
3. Common Conditions for Brufen 400 mg
3.1 Headaches & Migraines
Tension-type headaches are well-treated with Brufen. It also assists migraine patients in alleviating pain and accompanying inflammation by inhibiting prostaglandin release.
3.2 Toothaches & Dental Discomfort
Brufen is regularly prescribed by dentists, particularly after an extraction. Its anti-inflammatory action reduces swelling, as well as pain.
3.3 Muscle Aches & Soreness
Perfect for gym soreness, muscle strain, or minor sports injury. The anti-inflammatory action addresses inflammation in underlying tissue, rather than pain.
3.4 Menstrual Cramps (Dysmenorrhea)
Brufen eases cramps by blocking prostaglandins in the uterus that bring on painful contractions. Frequently more effective than ordinary painkillers.
3.5 Back Pain & Sciatica
Brufen can ease inflammation around spinal nerves or muscles. Best for temporary or flare-up use.
3.6 Low-Grade Fever
Low fevers below 102 °F (39 °C) may be treated with OTC doses of Brufen. One dose of 400 mg lowers body temperature without prescription drugs.
4. Dosage Guidelines
4.1 Adult Standard Dose
Single dose: 400 mg tablet
Frequency: Every 6–8 hours as needed
Maximum OTC dose: 1200 mg/day (<3 tablets)
4.2 When Prescription Dose Is Needed
For moderate to severe pain or inflammatory conditions (such as arthritis), doctors may recommend doses up to 2400 mg/day in divided intervals.
4.3 Taking Brufen Correctly
Take with food or milk to minimize stomach upset
Stay hydrated to protect kidney function
Avoid alcohol during use
Use the lowest effective dose—long-term NSAID use increases risk of side effects
4.4 Special Population Notes
Adolescents (12–17): Use under medical advice, typical dose 200–400 mg
Elderly: Start low, monitor for GI/renal side effects
Pregnancy: Avoid during the third trimester; consult your OB-GYN
5. Benefits of Brufen 400 mg
Fast-acting: Typically works within 30–60 minutes
Dual benefit: Tackles inflammation and pain
Well-supported: Long safety track record when used correctly
Seamless dosing: Covers mild to moderate pain without prescription
Flexible: Useful for various pains—from headaches to menstrual discomfort
6. Safety Considerations
6.1 Potential Side Effects
Common: heartburn, mild nausea, dizziness
Serious (less common): ulcers, kidney issues, bleeding, allergic reactions
6.2 Who Should Be Cautious
Avoid or seek advice if you have:
History of stomach ulcers or GI bleeding
Chronic kidney or liver conditions
Heart disease or hypertension
Pregnancy (3rd trimester)
Blood thinner therapy or other NSAIDs/steroids
6.3 Drug Interactions
Brufen interaction concerns:
Blood thinners (e.g., warfarin)
Blood pressure meds (ACE inhibitors, diuretics)
Other NSAIDs or corticosteroids
7. Tips for Optimizing Pain Relief
Start early: For migraines, take at pain onset
Combine with paracetamol or topical treatments (NSAID gel)
Add self-care: ice, heat, rest, stretching
Track dose timing: use reminders to avoid overdose
Consult a doctor for pain lasting beyond 7–10 days
8. Case Scenarios
Case 1: Weekend Headache
Take 400 mg at first twinge, drink water, rest. Add paracetamol if needed after 4–6 hours.
Case 2: Post-Gym Pain
400 mg after workout with food; apply ice and stretch the following day.
Case 3: Period Cramps
Start one tablet when cramps begin. Repeat every 6–8 hours for 1–2 days while symptoms persist. Avoid on empty stomach.
9. When to See a Doctor
Consult a healthcare provider if:
Pain lasts beyond 10 days
Fever remains elevated (>102 °F) for more than 3 days
GI symptoms or blood in stool/vomit
Allergic reactions
Chronic conditions requiring regular NSAID use
